182 research outputs found
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Control Theoretic Approaches to Congestion Pricing for High-occupancy Toll Lanes
The purpose of this study is to propose control theoretic approaches for high-occupancy toll (HOT) lanes operation. This dissertation considers different operation objectives, and provides pricing schemes for HOT lanes accordingly.To improve the system performance, the study first proposes a simultaneous estimation and control method for the same system as that in (Yin and Lou, 2009). An integral controller is applied to estimate the average value of time (VOT) of SOVs, and the dynamic prices are calculated based on the logit model. The closed-loop system is proved to be stable and guaranteed to converge to the optimal state both analytically and numerically. Two convergence patterns, Gaussian or exponential, are revealed. The effect of the scale parameter in the logit model is also examined.Then, a new lane choice model, i.e., the vehicle-based user equilibrium principle, is proposed to capture the lane choice of SOVs. A general lane choice model is derived based on the characteristics of the logit and the vehicle-based UE model. An insight regarding the dynamic price is obtained by analytically solving the optimal dynamic prices with constant demands of HOVs and SOVs, and then a feedback controller is designed to determine the dynamic prices without knowing SOVs’ lane choice models, but to satisfy the two control objectives: maximizing the flow-rate but not forming a queue on the HOT lanes. If the type of the lane choice model is given, the distribution of VOTs of the SOVs can be estimated.Next, an optimal control problem is proposed to examine the statement that revenue maximization should generally coincide with the optimization of freeway performances, such as maximizing overall travel-time savings or throughput. Results show that operators need to make different strategies based on the traffic demand. In order to maximize the revenue, operators should set a higher price to make the HOT lanes underutilized if the demand of HOVs is low. However, if the demand of HOVs is high, operators need to set a lower price to attract more SOVs to create congestion on the HOT lanes.It has long been known that drivers’ departure time choice behavior is one fundamental cause of congestion. In the last part of this dissertation, pricing schemes are proposed to consider both lane choice and departure time choice. In the study period, the demands for the HOT and GP lanes are higher than their capacities, which means the whole freeway is congested. However, the congestion period on the HOT lanes is short than that on the GP lanes. So, the HOT lanes are “underutilized”. It turns out that flat (instead of dynamic) pricing schemes are able to meet the following two constraints: (1) the total travel time and scheduling cost is minimized; and (2) the costs for each non-switching and switching SOV are the same. We show that different revenue and tolling constrains for certain type of vehicles lead to different pricing schemes
Transferable Multi-Agent Reinforcement Learning with Dynamic Participating Agents
We study multi-agent reinforcement learning (MARL) with centralized training
and decentralized execution. During the training, new agents may join, and
existing agents may unexpectedly leave the training. In such situations, a
standard deep MARL model must be trained again from scratch, which is very
time-consuming. To tackle this problem, we propose a special network
architecture with a few-shot learning algorithm that allows the number of
agents to vary during centralized training. In particular, when a new agent
joins the centralized training, our few-shot learning algorithm trains its
policy network and value network using a small number of samples; when an agent
leaves the training, the training process of the remaining agents is not
affected. Our experiments show that using the proposed network architecture and
algorithm, model adaptation when new agents join can be 100+ times faster than
the baseline. Our work is applicable to any setting, including cooperative,
competitive, and mixed.Comment: 10 pages, 7 figure
Genetic Variation and Antioxidant Response Gene Expression in the Bronchial Airway Epithelium of Smokers at Risk for Lung Cancer
Prior microarray studies of smokers at high risk for lung cancer have demonstrated that heterogeneity in bronchial airway epithelial cell gene expression response to smoking can serve as an early diagnostic biomarker for lung cancer. As a first step in applying functional genomic analysis to population studies, we have examined the relationship between gene expression variation and genetic variation in a central molecular pathway (NRF2-mediated antioxidant response) associated with smoking exposure and lung cancer. We assessed global gene expression in histologically normal airway epithelial cells obtained at bronchoscopy from smokers who developed lung cancer (SC, n=20), smokers without lung cancer (SNC, n=24), and never smokers (NS, n=8). Functional enrichment analysis showed that the NRF2-mediated, antioxidant response element (ARE)-regulated genes, were significantly lower in SC, when compared with expression levels in SNC. Importantly, we found that the expression of MAFG (a binding partner of NRF2) was correlated with the expression of ARE genes, suggesting MAFG levels may limit target gene induction. Bioinformatically we identified single nucleotide polymorphisms (SNPs) in putative ARE genes and to test the impact of genetic variation, we genotyped these putative regulatory SNPs and other tag SNPs in selected NRF2 pathway genes. Sequencing MAFG locus, we identified 30 novel SNPs and two were associated with either gene expression or lung cancer status among smokers. This work demonstrates an analysis approach that integrates bioinformatics pathway and transcription factor binding site analysis with genotype, gene expression and disease status to identify SNPs that may be associated with individual differences in gene expression and/or cancer status in smokers. These polymorphisms might ultimately contribute to lung cancer risk via their effect on the airway gene expression response to tobacco-smoke exposure.Intramural Research Program of the National Institute of Environmental Health Sciences; National Institutes of Health (Z01 ES100475, U01ES016035, R01CA124640
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Reliability-oriented optimization of computation offloading for cooperative vehicle-infrastructure systems
Computation offloading is critical for mobile applications that are sensitive to computational power, while dynamic and random nature of vehicular networks makes it challenging to guarantee the reliability of vehicular computation offloading. In this letter, we propose a reliability-oriented stochastic optimization model based on dynamic programming for computation offloading in the presence of the deadline constraint on application execution. Specifically, a theoretical lower bound of the expected reliability of computation offloading is derived, and then an optimal data transmission scheduling mechanism is proposed to maximize the lower bound with consideration of randomness in vehicle-to-infrastructure (V2I) communications. Experimental results demonstrate that our mechanism can outperform the conventional scheme and benefits vehicular computation offloading in terms of reliability performance in stochastic situations
Macroscopic fundamental diagram with volume-delay relationship: model derivation, empirical validation and invariance property
This paper presents a macroscopic fundamental diagram model with volume-delay
relationship (MFD-VD) for road traffic networks, by exploring two new data
sources: license plate cameras (LPCs) and road congestion indices (RCIs). We
derive a first-order, nonlinear and implicit ordinary differential equation
involving the network accumulation (the volume) and average congestion index
(the delay), and use empirical data from a 266 km urban network to fit an
accumulation-based MFD with . The issue of incomplete traffic volume
observed by the LPCs is addressed with a theoretical derivation of the
observability-invariant property: The ratio of traffic volume to the critical
value (corresponding to the peak of the MFD) is independent of the (unknown)
proportion of those detected vehicles. Conditions for such a property to hold
is discussed in theory and verified empirically. This offers a practical way to
estimate the ratio-to-critical-value, which is an important indicator of
network saturation and efficiency, by simply working with a finite set of LPCs.
The significance of our work is the introduction of two new data sources widely
available to study empirical MFDs, as well as the removal of the assumptions of
full observability, known detection rates, and spatially uniform sensors, which
are typically required in conventional approaches based on loop detector and
floating car data.Comment: 31 pages, 17 figure
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An effective fuel level data cleaning and repairing method for vehicle monitor platform
With energy scarcity and environmental pollution becoming increasingly serious, the accurate estimation of fuel consumption of vehicles has been important in vehicle management and transportation planning towards a sustainable green transition. Fuel consumption is calculated by fuel level data collected from high precision fuel level sensors. However, in the vehicle monitor platform, there are many types of error in the data collection and transmission processes, such as the noise, interference, and collision errors are common in the high speed and dynamic vehicle environment. In this paper, an effective method for cleaning and repairing the fuel level data is proposed, which adopts the threshold to acquire abnormal fuel data, the time quantum to identify abnormal data, and linear interpolation based algorithm to correct data errors. Specifically, a modified Gaussian Mixture Model (GMM) based on the synchronous iteration method is proposed to acquire the thresholds, which uses the Particle Swarm Optimization (PSO) algorithm and the steepest descent algorithm to optimize the parameters of GMM. The experiment results based on the fuel level data of vehicles collected over one month prove the modified GMM is superior to GMM-EM on fuel level data, and the proposed method is effective for cleaning and repairing outliers of fuel level data
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A microbial inspired routing protocol for VANETs
We present a bio-inspired unicast routing protocol for vehicular Ad Hoc Networks which uses the cellular attractor selection mechanism to select next hops. The proposed unicast routing protocol based on attractor selecting (URAS) is an opportunistic routing protocol, which is able to change itself adaptively to the complex and dynamic environment by routing feedback packets. We further employ a multi-attribute decision-making strategy, the Technique for Order Preference by Similarity to an Ideal Solution (TOPSIS), to reduce the number of redundant candidates for next-hop selection, so as to enhance the performance of attractor selection mechanism. Once the routing path is found, URAS maintains the current path or finds another better path adaptively based on the performance of current path, that is, it can self-evolution until the best routing path is found. Our simulation study compares the proposed solution with the state-of-the-art schemes, and shows the robustness and effectiveness of the proposed routing protocol and the significant performance improvement, in terms of packet delivery, end-to-end delay, and congestion, over the conventional method
Divergent Evolution of Human p53 Binding Sites: Cell Cycle Versus Apoptosis
The p53 tumor suppressor is a sequence-specific pleiotropic transcription factor that coordinates cellular responses to DNA damage and stress, initiating cell-cycle arrest or triggering apoptosis. Although the human p53 binding site sequence (or response element [RE]) is well characterized, some genes have consensus-poor REs that are nevertheless both necessary and sufficient for transactivation by p53. Identification of new functional gene regulatory elements under these conditions is problematic, and evolutionary conservation is often employed. We evaluated the comparative genomics approach for assessing evolutionary conservation of putative binding sites by examining conservation of 83 experimentally validated human p53 REs against mouse, rat, rabbit, and dog genomes and detected pronounced conservation differences among p53 REs and p53-regulated pathways. Bona fide NRF2 (nuclear factor [erythroid-derived 2]-like 2 nuclear factor) and NFκB (nuclear factor of kappa light chain gene enhancer in B cells) binding sites, which direct oxidative stress and innate immunity responses, were used as controls, and both exhibited high interspecific conservation. Surprisingly, the average p53 RE was not significantly more conserved than background genomic sequence, and p53 REs in apoptosis genes as a group showed very little conservation. The common bioinformatics practice of filtering RE predictions by 80% rodent sequence identity would not only give a false positive rate of ∼19%, but miss up to 57% of true p53 REs. Examination of interspecific DNA base substitutions as a function of position in the p53 consensus sequence reveals an unexpected excess of diversity in apoptosis-regulating REs versus cell-cycle controlling REs (rodent comparisons: p < 1.0 e−12). While some p53 REs show relatively high levels of conservation, REs in many genes such as BAX, FAS, PCNA, CASP6, SIVA1, and P53AIP1 show little if any homology to rodent sequences. This difference suggests that among mammalian species, evolutionary conservation differs among p53 REs, with some having ancient ancestry and others of more recent origin. Overall our results reveal divergent evolutionary pressure among the binding targets of p53 and emphasize that comparative genomics methods must be used judiciously and tailored to the evolutionary history of the targeted functional regulatory regions
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Channel access optimization with adaptive congestion pricing for cognitive vehicular networks: an evolutionary game approach
Cognitive radio-enabled vehicular nodes as unlicensed users can competitively and opportunistically access the radio spectrum provided by a licensed provider and simultaneously use a dedicated channel for vehicular communications. In such cognitive vehicular networks, channel access optimization plays a key role in making the most of the spectrum resources. In this paper, we present the competition among self-interest-driven vehicular nodes as an evolutionary game and study fundamental properties of the Nash equilibrium and the evolutionary stability. To deal with the inefficiency of the Nash equilibrium, we design a delayed pricing mechanism and propose a discretized replicator dynamics with this pricing mechanism. The strategy adaptation and the channel pricing can be performed in an asynchronous manner, such that vehicular users can obtain the knowledge of the channel prices prior to actually making access decisions. We prove that the Nash equilibrium of the proposed evolutionary dynamics is evolutionary stable and coincides with the social optimum. Besides, performance comparison is also carried out in different environments to demonstrate the effectiveness and advantages of our method over the distributed multi-agent reinforcement learning scheme in current literature in terms of the system convergence, stability and adaptability
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Reliability-optimal cooperative communication and computing in connected vehicle systems
The emergence of vehicular networking enables distributed cooperative computation among nearby vehicles and infrastructures to achieve various applications that may need to handle mass data by a short deadline. In this paper, we investigate the fundamental problems of a cooperative vehicle-infrastructure system (CVIS): how does vehicular communication and networking affect the benefit gained from cooperative computation in the CVIS and what should a reliability-optimal cooperation be? We develop an analytical framework of reliability-oriented cooperative computation optimization, considering the dynamics of vehicular communication and computation. To be specific, we propose stochastic modeling of V2V and V2I communications, incorporating effects of the vehicle mobility, channel contentions and fading, and theoretically derive the probability of successful data transmission. We also formulate and solve an execution time minimization model to obtain the success probability of application completion with the constrained computation capacity and application requirements. By combining these models, we develop constrained optimizations to maximize the coupled reliability of communication and computation by optimizing the data partitions among different cooperators. Numerical results confirm that vehicular applications with a short deadline and large processing data size can better benefit from the cooperative computation rather than non-cooperative solutions
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